Mechanosensing and chemotaxis (past)
The social amoeba Dictyostelium discoideum performs chemotaxis under starvation conditions, aggregating towards clusters of cells following waves of the signaling molecule cAMP. We developed a biophysical model to integrate the signal relay network with the chemotaxis network to explain the perfect adaptation and timescale matching observed in Dictyostelium chemotaxis.
David J. Lemon, Xingbo Yang, Pragya Srivastava, Yan-Yeung Luk, Anthony G. Garza
Scientific Reports, 2017 Aug 11, p. 7643
Daniel P. Shams, Xingbo Yang, Pankaj Mehta, David J. Schwab
Physical Review E, vol. 101(6), 2020 May 11, pp. 62410-62410